Charles Darwin

His mother Susannah died in 1818 at age 52, probably of an ulcer or stomach cancer.

An excerpt from the article 25 facts about Charles Darwin

Charles was only nine years old at the time of his mother's death, but by then his father had already decided his fate. Robert Darwin was a successful and popular physician, and he chose this career path for his son as well. Having assumed full responsibility for Charles, he steered him toward medicine, although Darwin had shown an interest in natural history and collecting even as a young boy.