These include leopards, hyenas, wild dogs, lions, caracals, cheetahs, jackals, and baboons, as well as eagles, hawks, pythons, and humans.
To ward off predation, dik-diks are fast runners, reaching up to 42 km/h speed, and have excellent eyesight. Both males and females make a piercing, whistling sound (different from the alarming one) that can warn other animals of the danger.