StarCraft

StarCraft takes place in space and... space it has visited.

An excerpt from the article 15 facts about StarCraft

In 1999, NASA astronaut Daniel Barry took a copy of the first game on his voyage to the International Space Station, giving it more than 150 laps of our planet before the mission was over.

Currently, the “first StarCraft disc in space” is housed at Blizzard’s headquarters.