In addition to humans, they are threatened by sharks, crocodiles, and alligators, but this is rare because they mostly occupy different habitats. In the case of West African manatees, they are mostly threatened by crocodiles.
Humans hunt manatees primarily for their meat. As they are slow swimmers, they are easy prey. Even though manatees are classified as species at risk of extinction, poachers constantly hunt them for meat, oil, bones, and skin.