Panama

The Darién Gap is a break on the Pan-American Road.

An excerpt from the article 22 facts about Panama

The Pan-American Road or Pan-American Highway is a road system of some 30.000 kilometers that crosses all of North, Central, and South America-from Alaska to Patagonia. A breach in it is the Darién Gap, where there is no circular road for about 100 kilometers. The only possible route from Panama to Colombia is by sea. On the Panamanian side, the endpoint of the road is the town of Yaviza, and on the South American side is the town of Turbo.

The area is used by Colombian guerrillas and drug traffickers.