Florence

During the times of Emperor Hadrian, the city was connected to Rome by the Via Cassia road.

An excerpt from the article 34 facts about Florence

Current Florence was founded by Julius Caesar in 59 BC as a settlement for veterans and was called Fluentia, as it was founded between two rivers. Later the name was changed to Florentia, which meant "city of prosperity".

Its location along Via Cassia, the main route connecting Rome with the north, in the fertile Arno Valley, meant that the settlement quickly became an important trading center.