In the 1st century AD, the Christian faith reached Ephesus.

An excerpt from the article 30 facts about Epheseus

A conflict began between the Christian god and the pagan gods. One of the people involved in this conflict was Saint Paul of Tarsus, who probably visited Ephesus three times on his missionary mission and taught the Ephesians. A conflict of interests arose because the number of people adopting the new faith was systematically increasing, which affected the profits of local producers and sellers of devotional items related to the cult of Artemis.