Saint Paul had to escape from Ephesus.

An excerpt from the article 30 facts about Epheseus

While preaching by Saint Paul in the Grand Theater, one of the craftsmen, the jeweler Demetrius, who made miniatures of the temple of Artemis, having heard Paul's words that gods appointed by people cannot be "Gods" and cannot be "holy", organized a demonstration. Together with the outraged craftsmen, he stormed into the Grand Theater, shouting: "Artemis of Ephesus is great!" Confusion ensued, and several companions of St. Paul were kidnapped by the crowd. The local secretary, Saint, managed to calm down the situation. Paul had to leave Ephesus and go to Macedonia.