Nicotine binds permanently to nicotinic receptors in nerve cells, disturbing their metabolism. Initially, there is a feeling of lightness, then a change in perception, a change in the perception of the surroundings, photophobia, fatigue, lack of energy, a feeling of detachment from reality, thoughtfulness, vomiting, and diarrhea. In even higher doses, the field of vision becomes blurred and hallucinations may appear - usually black and white images. At extreme doses, loss of consciousness, convulsions, and death occur.