Ghent in the 15th century was a city of culture and an important scientific center.

An excerpt from the article 44 facts about Ghent

It was there that the van Eyck brothers created the Altarpiece of the Mystic Lamb in 1432, and it was there that Hugo van der Goes (master of Dutch Renaissance painting, the most prominent artist of the generation of so-called Dutch primitivists) worked. The city had many scholars (Erasmus of Rotterdam), but also many centers where one could receive education (about 300 students attended the gymnasium), and private lessons were common.