Lake Huron

The French barque Le Griffon was the first European ship to sink in the lake due to a raging storm.

An excerpt from the article 20 facts about Lake Huron
It was also the first European vessel to sail the Great Lakes. To date, the wreck of Le Griffon, referred to as the "Holy Grail" of Great Lakes shipwreck hunters, has not been found. A similar shipwreck was discovered by sonar scan near Poverty Island in 2001 but is still awaiting identification. Additional difficulties arise from the fact that the wreck lies under several meters of sediment.