The bufotoxin produced by the toad's skin is very dangerous to animals and can kill them quickly.
Dogs tend to be poisoned because they often bite or lick cane toads. Exposure to the toxin can cause drooling, loss of coordination, head shaking and convulsions.
Initially, their musculoskeletal system was adapted for terrestrial bipedal saltation, common among marsupials. They are capable of climbing trees up to 1,5 meters.